:root{--bg: #eef1f2;--surface: #ffffff;--surface-subtle: #f5f7f8;--surface-strong: #ffffff;--line: #d4dce0;--line-strong: #b0bec5;--ink: #102b33;--muted: #5b6e73;--text-disabled: #8a9ba0;--accent: #087f8c;--accent-hover: #066b76;--accent-soft: rgba(8, 127, 140, .11);--warning: #9a4b25;--warning-soft: rgba(154, 75, 37, .11);--success: #28775b;--success-soft: rgba(40, 119, 91, .1);--shadow: none;--shadow-raised: 0 10px 28px rgba(16, 43, 51, .16);--shadow-overlay: 0 12px 32px rgba(16, 43, 51, .18);--font-sans: "IBM Plex Sans", Inter, ui-sans-serif, system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;--font-display: "IBM Plex Sans Condensed", "Arial Narrow", var(--font-sans);--font-mono: "IBM Plex Mono", "SFMono-Regular", Consolas, monospace;--radius-sm: 3px;--radius-md: 4px;--radius-lg: 6px;--space-1: 4px;--space-2: 8px;--space-3: 12px;--space-4: 16px;--space-5: 20px;--space-6: 24px;--space-8: 32px;--control-height-compact: 32px;--control-height: 36px;--control-height-comfortable: 40px;--focus-ring-color: rgba(8, 127, 140, .28);--focus-ring-width: 3px;--focus-ring-offset: 2px;--alignment-row-height: 28px;--alignment-header-height: 42px;--alignment-visible-rows: 30;--workspace-split-min: 1200px;--workspace-chrome-offset: 112px;--workspace-lower-peek: 52px;--workspace-main-height: max( 420px, calc(100dvh - var(--workspace-chrome-offset) - var(--workspace-lower-peek)) )}.ui-button{display:inline-flex;align-items:center;justify-content:center;gap:6px;min-height:var(--control-height-compact);padding:4px 10px;border:1px solid var(--line);border-radius:var(--radius-sm);background:var(--surface-strong);color:var(--ink);font-size:.82rem;font-weight:650;line-height:1.2;cursor:pointer;white-space:nowrap}.ui-button:hover:not(:disabled){border-color:var(--line-strong);background:var(--surface-subtle);color:var(--accent-hover)}.ui-button:disabled{cursor:not-allowed;opacity:.5;color:var(--text-disabled)}.ui-button--primary{border-color:var(--accent);background:var(--accent);color:#fff}.ui-button--primary:hover:not(:disabled){border-color:var(--accent-hover);background:var(--accent-hover);color:#fff}.ui-button--secondary{border-color:var(--line);background:var(--surface-strong);color:var(--ink)}.ui-button--quiet{border-color:var(--line);background:var(--surface-strong);color:var(--muted)}.ui-button--quiet:hover:not(:disabled){color:var(--accent-hover);background:var(--surface-subtle)}.ui-button--danger{border-color:#9a4b2573;background:var(--warning-soft);color:var(--warning)}.ui-button--danger:hover:not(:disabled){border-color:var(--warning);background:#9a4b2529;color:var(--warning)}.ui-button--active{border-color:var(--accent);background:var(--accent);color:#fff}.ui-button--active:hover:not(:disabled){border-color:var(--accent-hover);background:var(--accent-hover);color:#fff}.ui-button--sm{min-height:28px;padding:2px 8px;font-size:.78rem}.ui-button--lg{min-height:var(--control-height);padding:6px 12px;font-size:.88rem}.ui-button svg{flex:0 0 auto}.ui-icon-button{display:inline-flex;align-items:center;justify-content:center;width:var(--control-height-compact);height:var(--control-height-compact);padding:0;border:1px solid var(--line);border-radius:var(--radius-sm);background:var(--surface-strong);color:var(--muted);cursor:pointer}.ui-icon-button:hover:not(:disabled){color:var(--ink);border-color:var(--line-strong);background:var(--surface-subtle)}.ui-icon-button:disabled{cursor:not-allowed;opacity:.5}.ui-icon-button--quiet{border-color:transparent;background:transparent}.ui-icon-button--quiet:hover:not(:disabled){background:var(--accent-soft);color:var(--accent-hover);border-color:transparent}.ui-icon-button--active{border-color:var(--accent);background:var(--accent);color:#fff}.ui-icon-button--active:hover:not(:disabled){border-color:var(--accent-hover);background:var(--accent-hover);color:#fff}.ui-field{display:grid;gap:5px;min-width:0;color:var(--muted);font-size:.72rem;font-weight:700;letter-spacing:.04em;text-transform:uppercase}.ui-field--inline{display:inline-flex;align-items:center;gap:6px;grid-template-columns:none}.ui-field__label{flex:0 0 auto}.ui-field__control{min-width:0}.ui-input,.ui-select,.ui-search{width:100%;min-height:var(--control-height-compact);padding:4px 8px;border:1px solid var(--line);border-radius:var(--radius-sm);background:var(--surface-strong);color:var(--ink);font-size:.86rem;font-weight:620;letter-spacing:0;text-transform:none}.ui-select{padding-right:28px;cursor:pointer}.ui-input:hover,.ui-select:hover,.ui-search:hover{border-color:var(--line-strong)}.ui-input:disabled,.ui-select:disabled,.ui-search:disabled{cursor:not-allowed;opacity:.55;color:var(--text-disabled)}.ui-checkbox{display:inline-flex;align-items:center;gap:8px;min-height:var(--control-height-compact);color:var(--muted);font-size:.9rem;font-weight:650;letter-spacing:0;text-transform:none;cursor:pointer}.ui-checkbox input{width:16px;height:16px;margin:0;cursor:pointer;accent-color:var(--accent)}.ui-checkbox:has(input:disabled){cursor:not-allowed;opacity:.55}.ui-segmented{display:inline-flex;align-items:center;gap:6px;min-width:0}.ui-segmented__label{color:var(--muted);font-size:.72rem;font-weight:700;letter-spacing:.04em;text-transform:uppercase;white-space:nowrap}.ui-segmented__group{display:inline-grid;grid-auto-flow:column;grid-auto-columns:minmax(0,1fr);gap:2px;padding:2px;border:1px solid var(--line);border-radius:var(--radius-md);background:var(--surface-subtle)}.ui-segmented__option{min-height:var(--control-height-compact);padding:0 10px;border:0;border-radius:var(--radius-sm);background:transparent;color:var(--muted);cursor:pointer;font-size:.8rem;font-weight:680;white-space:nowrap}.ui-segmented__option:hover:not(:disabled):not([aria-checked=true]){color:var(--ink);background:var(--surface)}.ui-segmented__option[aria-checked=true]{background:var(--surface-strong);color:var(--accent-hover);border:1px solid var(--line)}.ui-segmented__option:disabled{cursor:not-allowed;opacity:.44}.ui-tabs{display:flex;flex-direction:column;min-height:0;min-width:0}.ui-tabs__list{display:inline-grid;grid-auto-flow:column;grid-auto-columns:minmax(0,1fr);gap:4px;width:fit-content;max-width:100%;padding:4px;border:1px solid var(--line);border-radius:var(--radius-md);background:var(--surface-subtle)}.ui-tabs__list--stretch{width:100%}.ui-tabs__tab{border:1px solid transparent;border-radius:var(--radius-sm);background:transparent;color:var(--muted);min-height:var(--control-height-compact);padding:7px 12px;font-size:.9rem;font-weight:650;cursor:pointer}.ui-tabs__tab:hover:not(:disabled):not([aria-selected=true]){background:var(--surface);color:var(--ink)}.ui-tabs__tab[aria-selected=true]{background:var(--surface-strong);color:var(--accent-hover);border:1px solid var(--line)}.ui-tabs__tab:disabled{cursor:not-allowed;opacity:.5}.ui-tabs__panel{min-height:0;min-width:0}.ui-tabs__panel[hidden]{display:none}.ui-pane{display:grid;grid-template-rows:auto minmax(0,1fr);border:1px solid var(--line);border-radius:var(--radius-lg);background:var(--surface);overflow:hidden;min-height:0;min-width:0}.ui-pane__body{min-height:0;min-width:0;overflow:hidden}.ui-pane-header{display:flex;justify-content:space-between;gap:18px;align-items:flex-start;padding:12px 14px 10px;border-bottom:1px solid var(--line);background:var(--surface-subtle)}.ui-pane-header__main{min-width:0}.ui-pane-header__eyebrow{margin:0;letter-spacing:.14em;text-transform:uppercase;color:var(--accent-hover);font-size:.7rem;font-weight:750}.ui-pane-header__title{margin:4px 0 0;font-family:var(--font-display);font-size:1.25rem;font-weight:720;line-height:1.15;letter-spacing:-.025em}.ui-pane-header__subtitle{margin:6px 0 0;color:var(--muted);font-size:.88rem;line-height:1.45}.ui-pane-header__meta{max-width:22rem;margin:0;color:var(--muted);font-size:.88rem;line-height:1.5;text-align:right}.ui-pane-header__actions{display:flex;flex-wrap:wrap;justify-content:flex-end;gap:8px;min-width:0}.ui-empty{display:grid;place-items:center;gap:6px;min-height:120px;padding:24px;color:var(--muted);text-align:center}.ui-empty__title{margin:0;color:var(--ink);font-size:.95rem;font-weight:700}.ui-empty__body{margin:0;max-width:28rem;font-size:.88rem;line-height:1.45}.ui-status{margin-top:12px;padding:12px 14px;border:1px solid var(--line);border-radius:var(--radius-md);font-weight:620;line-height:1.4}.ui-status--info{background:var(--accent-soft);color:var(--accent-hover);border-color:#087f8c47}.ui-status--warning{background:var(--warning-soft);color:var(--warning);border-color:#9a4b2547}.ui-status--success{background:var(--success-soft);color:var(--success);border-color:#28775b47}.ui-status--error{background:var(--warning-soft);color:var(--warning);border-color:#9a4b2566}.ui-legend{display:flex;flex-wrap:wrap;gap:8px 12px;margin:0;padding:0;list-style:none}.ui-legend__item{display:inline-flex;align-items:center;gap:6px;min-height:24px;color:var(--ink);font-size:.82rem;font-weight:620}.ui-legend__swatch{position:relative;display:inline-flex;align-items:center;justify-content:center;flex:0 0 auto;width:14px;height:14px;border-radius:var(--radius-sm);border:1px solid rgba(16,43,51,.18);box-sizing:border-box}.ui-legend__swatch--solid{border-style:solid;border-width:2px;border-color:#102b33bf}.ui-legend__swatch--dashed{border-style:dashed;border-width:2px;border-color:#102b33a6}.ui-legend__swatch--dotted{border-style:dotted;border-width:2px;border-color:#102b338c}.ui-legend__swatch--hatched{background-image:repeating-linear-gradient(-45deg,rgba(16,43,51,.35),rgba(16,43,51,.35) 1px,transparent 1px,transparent 3px)!important}.ui-legend__mark{font-size:.62rem;font-weight:800;line-height:1;color:#102b33;text-shadow:0 0 2px rgba(255,255,255,.9)}.ui-legend__label{line-height:1.2}.ui-tooltip{display:inline-flex;max-width:100%}.ui-tooltip__content{position:fixed;z-index:10000;box-sizing:border-box;width:max-content;max-width:min(320px,calc(100vw - 16px));padding:6px 8px;border:1px solid rgba(255,255,255,.12);border-radius:var(--radius-sm);background:#102b33;color:#f7fbfb;font-size:.75rem;font-weight:600;line-height:1.35;text-align:left;white-space:normal;pointer-events:none;box-shadow:var(--shadow-overlay)}@layer reset,shell,panels,chrome,responsive;@layer panels{.genotype-panel-header{align-items:center;gap:12px;padding-bottom:10px}.genotype-panel-header h2{margin:0}.genotype-select-group{display:inline-flex;flex-direction:row;flex-wrap:nowrap;align-items:center;gap:6px;white-space:nowrap}.genotype-select-group .ui-tooltip{flex:0 0 auto;max-width:none}.genotype-sort{display:inline-flex;align-items:center;justify-content:center;gap:4px;margin:0;padding:0;border:0;background:transparent;color:inherit;font:inherit;font-weight:720;letter-spacing:.02em;text-transform:uppercase;cursor:pointer;white-space:nowrap}.genotype-sort:hover,.genotype-sort-active{color:var(--accent-hover)}.genotype-sort-indicator{font-size:.72rem;line-height:1}.genotype-body{padding:0 12px 12px;overflow:visible}.genotype-table-wrap{width:fit-content;max-width:100%;max-height:420px;overflow-x:scroll;overflow-y:auto;border:1px solid var(--line);border-radius:var(--radius-md);background:var(--surface-strong);scrollbar-width:auto;scrollbar-color:rgba(8,127,140,.72) rgba(16,43,51,.1)}.genotype-table-wrap::-webkit-scrollbar{width:12px;height:12px}.genotype-table-wrap::-webkit-scrollbar-track{background:#102b3314;border-radius:0 0 var(--radius-md) 0}.genotype-table-wrap::-webkit-scrollbar-thumb{background:#087f8c8c;border:2px solid transparent;border-radius:8px;background-clip:padding-box}.genotype-table-wrap::-webkit-scrollbar-thumb:hover{background:#087f8cc7;border:2px solid transparent;background-clip:padding-box}.genotype-table-wrap::-webkit-scrollbar-corner{background:#102b3314}.genotype-table{width:max-content;table-layout:auto;border-collapse:collapse;font-size:.86rem}.genotype-table th,.genotype-table td{padding:9px 10px;border-bottom:1px solid rgba(16,43,51,.07);text-align:left;vertical-align:middle}.genotype-table th{position:sticky;top:0;z-index:1;background:#f3f7f7;color:var(--muted);font-size:.78rem;font-weight:720;letter-spacing:.02em;text-transform:uppercase}.genotype-table tbody tr:hover{background:#087f8c0a}.genotype-row-selected{background:#087f8c1a!important;box-shadow:inset 4px 0 0 0 var(--accent);outline:1px solid rgba(8,127,140,.35);outline-offset:-1px}.genotype-row-selected[data-filter-mode=match]{box-shadow:inset 3px 0 0 0 var(--accent),inset 6px 0 #ffffffd9,inset 9px 0 0 0 var(--accent)}.genotype-row-status{display:inline-flex;align-items:center;min-height:24px;padding:0 8px;border:1px solid rgba(8,127,140,.35);border-radius:999px;background:#087f8c14;color:var(--accent-hover);font-size:.72rem;font-weight:780;letter-spacing:.04em;text-transform:uppercase;white-space:nowrap}.genotype-count{width:72px;font-variant-numeric:tabular-nums;font-weight:720;color:var(--ink)}.genotype-count-match{color:var(--accent-hover)}.genotype-fill{display:inline-flex;align-items:center;min-height:24px;padding:2px 8px;border-radius:999px;font-size:.78rem;font-weight:700;white-space:nowrap}.genotype-fill-complete{border:1px solid rgba(40,119,91,.22);background:var(--success-soft);color:var(--success)}.genotype-fill-partial{border:1px solid rgba(16,43,51,.12);background:#eef2f3;color:var(--muted)}.genotype-origin-legend{display:flex;flex-wrap:wrap;align-items:center;gap:6px;padding:10px 12px;border-bottom:1px solid rgba(16,43,51,.08);background:#f8fbfb}.genotype-origin-legend-label{margin-right:4px;color:var(--muted);font-size:.75rem;font-weight:760;letter-spacing:.03em;text-transform:uppercase}.genotype-origin-legend-item{display:inline-flex;align-items:center;min-height:24px;padding:2px 9px 2px 10px;border:1px solid rgba(16,43,51,.12);border-radius:999px;color:var(--ink);font-size:.78rem;font-weight:760;letter-spacing:.02em;white-space:nowrap;cursor:default}.genotype-col-origins{min-width:0}.genotype-cassette{--genotype-cell-width: 5.1rem;display:grid;grid-template-columns:repeat(8,var(--genotype-cell-width));width:max-content;gap:0;border:1px solid rgba(16,43,51,.12);border-radius:var(--radius-sm);overflow:hidden;background:var(--surface-strong)}.genotype-cassette-header{border-color:#102b3324;background:transparent}.genotype-cell{display:block;box-sizing:border-box;width:var(--genotype-cell-width);min-width:0;min-height:28px;padding:6px 4px;border-right:1px solid rgba(16,43,51,.08);color:var(--ink);font-size:.72rem;font-weight:720;letter-spacing:.01em;line-height:1.15;text-align:center;text-transform:none;white-space:nowrap;overflow:hidden;text-overflow:ellipsis}.genotype-cell:last-child{border-right:none}.genotype-cell-label{min-height:22px;background:#102b330a;color:var(--muted);font-size:.68rem;font-weight:780;letter-spacing:.04em;text-transform:uppercase}button.genotype-cell-label{display:inline-flex;align-items:center;justify-content:center;gap:2px;margin:0;border:0;border-right:1px solid rgba(16,43,51,.08);border-radius:0;cursor:pointer;font:inherit;font-size:.68rem;font-weight:780;letter-spacing:.04em;text-transform:uppercase}button.genotype-cell-label:last-child{border-right:none}button.genotype-cell-label:hover,button.genotype-cell-label.genotype-sort-active{color:var(--accent-hover);background:#087f8c14}.genotype-cell-origin{background:#f7fafb}.genotype-cell-empty{background:#eef1f2;color:#9aa6ab;font-weight:600}.genotype-col-action{width:1%;padding-left:12px;text-align:left;white-space:nowrap;vertical-align:middle}.genotype-col-action .genotype-select-button{flex:0 0 auto;white-space:nowrap}}@layer panels{.history-title-block{display:flex;flex-direction:column;gap:2px;min-width:0}.history-grouping{margin:0;color:var(--muted);font-size:.82rem;font-weight:600;line-height:1.3}.history-grouping strong{color:var(--ink);font-weight:760}.history-controls{display:flex;flex-wrap:wrap;align-items:center;justify-content:flex-end;gap:10px 14px;min-width:0}.history-controls .ui-tooltip{display:inline-flex}.history-window-presets .ui-segmented__group,.history-value-mode .ui-segmented__group{flex-wrap:nowrap}.history-window-presets .ui-segmented__option,.history-value-mode .ui-segmented__option{min-height:28px;padding:2px 8px;font-size:.78rem}.history-control{display:inline-flex;align-items:center;gap:8px;min-height:32px;color:var(--muted);font-size:.9rem;font-weight:650;white-space:nowrap;cursor:help}.history-control--inline{gap:6px}.history-controls input[type=number]{width:4rem;min-width:0;min-height:32px;padding:4px 8px;border:1px solid var(--line);border-radius:var(--radius-sm);background:var(--surface-strong);color:var(--ink);box-sizing:border-box}.history-check{display:inline-flex;align-items:center;gap:8px;min-height:32px;color:var(--muted);font-size:.86rem;font-weight:650;cursor:pointer;-webkit-user-select:none;user-select:none}.history-check input{width:1rem;height:1rem;margin:0;accent-color:var(--accent)}.history-panel-header h2,.clock-panel-header h2,.geography-panel-header h2{margin:0}.history-controls .visually-hidden{position:absolute;width:1px;height:1px;padding:0;margin:-1px;overflow:hidden;clip:rect(0,0,0,0);white-space:nowrap;border:0}}@layer panels{.alignment-controls{display:flex;flex-wrap:wrap;justify-content:flex-end;align-items:flex-end;gap:10px;min-width:min(420px,100%)}.alignment-source-field{flex:0 1 auto;min-width:min(200px,100%)}.alignment-source-field.is-inactive{visibility:hidden;pointer-events:none}.alignment-controls label,.alignment-source-field .ui-field{display:grid;gap:5px;color:var(--muted);font-size:.76rem;font-weight:720;letter-spacing:.06em;text-transform:uppercase}.alignment-controls select,.alignment-source-field .ui-select{min-width:160px;max-width:240px;width:100%;min-height:34px;border:1px solid var(--line);border-radius:var(--radius-sm);background:var(--surface-strong);color:var(--ink);padding:5px 9px;text-transform:none;font-size:.88rem;font-weight:620;cursor:pointer}.alignment-controls select:hover,.alignment-source-field .ui-select:hover:not(:disabled){border-color:var(--line-strong)}.alignment-controls select:disabled,.alignment-source-field .ui-select:disabled{opacity:.55;cursor:not-allowed}.alignment-view-tabs{flex:0 0 auto;align-self:end}.alignment-shell{overflow:hidden;background:#fff}.custom-alignment{height:100%;overflow:auto;background:#fff;border-top:1px solid rgba(16,43,51,.08);scrollbar-width:auto;scrollbar-color:rgba(8,127,140,.72) rgba(16,43,51,.1)}.custom-alignment::-webkit-scrollbar{width:14px;height:14px}.custom-alignment::-webkit-scrollbar-track{background:#102b3314;border-radius:8px;border:1px solid rgba(16,43,51,.06)}.custom-alignment::-webkit-scrollbar-thumb{background:#087f8c9e;border-radius:8px;border:2px solid rgba(255,255,255,.65);background-clip:padding-box}.custom-alignment::-webkit-scrollbar-thumb:hover{background:#087f8ce0;border:2px solid rgba(255,255,255,.55);background-clip:padding-box}.custom-alignment::-webkit-scrollbar-corner{background:#102b330f}.alignment-grid{display:grid;grid-template-columns:var(--metadata-column-width, 280px) var(--sequence-column-width, minmax(0, 1fr));align-content:start;align-items:start;position:relative}.alignment-header{position:sticky;top:0;z-index:40;display:flex;align-items:center;flex:0 0 auto;padding:0 14px;height:42px;background:var(--surface-subtle);border-bottom:1px solid var(--line);font-size:.8rem;letter-spacing:.12em;text-transform:uppercase;color:var(--muted);box-sizing:border-box}.metadata-header{z-index:41;justify-content:space-between;gap:10px;border-right:1px solid rgba(16,43,51,.1)}.column-jump-form{display:flex;align-items:center;gap:5px;letter-spacing:0;text-transform:none}.column-jump-form label{display:flex;align-items:center;gap:4px;color:var(--muted);font-size:.72rem}.column-jump-form input{width:62px;height:26px;border:1px solid var(--line);border-radius:var(--radius-sm);background:var(--surface-strong);color:var(--ink);font:inherit;padding:0 6px}.column-jump-form button{height:26px;border:1px solid rgba(8,127,140,.26);border-radius:var(--radius-sm);background:var(--accent-soft);color:var(--accent);font:inherit;font-weight:700;padding:0 8px;cursor:pointer}.column-jump-form button:hover{border-color:var(--accent);background:#087f8c29}.sequence-header{padding:0;overflow:hidden;letter-spacing:0;text-transform:none;align-items:stretch}.sequence-header-layer{position:relative;flex:1 1 auto;width:100%;min-width:0;height:100%}.alignment-grid.genotype-mode .sequence-header{background:var(--surface-subtle);overflow:visible}.alignment-grid.genotype-mode{width:100%}.alignment-grid.genotype-mode .content-column{min-width:var(--genotype-column-width, 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